Computational and Applied Math Proseminar

Department of Mathematics and Statistics
Arizona State University

Thursday, November 13, 2003, 12:15 p.m. in GWC 604

Hongbin Guo

Department of Mathematics and Statistics

Clustering for three dimensional Kinetic PET Data

Abstract We present a fast Hierarchical linkage (HL) clustering technique for kinetic positron emission tomography (PET) data according to a dissimilarity measurement between time activity curves. Due to the huge size of PET data, the cost of conventional HL is too expensive to real applications. We suggest two strategies: significantly reduce the data size, about 75%, by thresholding and a preclustering technique and followed by a slice by slice two dimensional HL clustering. The efficiency and superiority is validated by comparison of the results for FDG-PET brain data of 13 healthy subjects.
This is joint work with R. Renaut and K. Chen

For further information please contact: mittelmann@asu.edu